All concepts, explanations, trials, and studies have been re-written in plain English and may contain errors. I am not a doctor ----------------------------------------------------------- NOTE: You can make the print bigger with the font button on your browser! (It's usually a big "A") ---------------------------------------------------------- Creatine and Kidney Function in Healthy Athletes Doctors often claim kidney function can be reduced by oral creatine supplements. We studied kidney function in healthy people taking creatine supplements. Creatinine and urea (kidney function tests), and blood albumin (liver function test) were measured in people taking oral creatine, who had taken it for 10 months to 5 years. We also measured the same levels in a control group not taking creatine. There was no significant difference between groups in any test. Kidney function was not affected by the oral creatine supplement. Source: Med Sci Sports Exerc. 1999 Aug;31(8):1108-10. Title: Long-term oral creatine supplementation does not impair renal function in healthy athletes. Authors: Poortmans JR, Francaux M. PMID: 10449011. Creatine and Kidney Function in Football Players We studied long-term creatine supplement use in football players. Blood tests for liver and kidney function measured what effect the supplement had. Twenty-three members of an NCAA Division II American football team (ages 19 to 24 years) with at least 2 years of strength training experience were divided into a creatine monohydrate group (10 men) and a control group (13 men). Creatine players took 5 to 20 grams creatine daily (average 10 grams daily) for from 3 months to 5.6 years (average 2.35 years). Blood tests included albumin, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, bilirubin, urea, and creatinine. The creatine and non-creatine groups had similar test results. It appears that oral creatine use has no long-term harmful effects on kidney or liver function in highly trained college athletes. Title: Effects of long-term creatine supplementation on liver and kidney functions in American college football players. Authors: Mayhew DL, Mayhew JL, Ware JS. Source: Int J Sport Nutr Exerc Metab. 2002 Dec;12(4):453-60.